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Hi Mike Jaffal,
Welcome to Microsoft Q&A Forum!
Have a good day and I hope you're doing well!
I’m really sorry you’re running into this. It’s understandably frustrating when Word or Excel won’t open or show “Not Responding.”
Have you already tried completely uninstalling Office from your Mac and then reinstalling the latest version of Microsoft 365? This often resolves issues caused by older or corrupted components. You can find Microsoft’s official update and download history for Office on Mac here: Update history for Office for Mac
After reinstalling, please restart your Mac and try opening Word or Excel again.
If you use OneDrive or any other cloud storage service, try pausing or quitting them temporarily before launching Word or Excel. This helps check whether cloud sync might be interfering when the apps start.
There’s also an Apple Community discussion on a similar “Office 365 not responding” issue that might offer additional insight: Apple Community discussion
Note: Microsoft is providing this information as a convenience to you. These sites are not controlled by Microsoft, and Microsoft cannot make any representations regarding the quality, safety, or suitability of any software or information found there. Please ensure that you fully understand the risks before using any suggestions from the above link.
I hope this helps partially. If you have any additional information, please share. That will help me gain more insight and suggest a more precise troubleshooting path. If I’ve misunderstood or anything is unclear, feel free to reach out.
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