The Outlook app will not respond or open in my profile.

It sounds like you are experiencing issues with Outlook not responding or opening in your profile, while it works fine in another profile. Here are some steps you can take to troubleshoot the problem:

1. Create a New Outlook Profile: Since you've mentioned trying to set up a new profile without success, ensure that you follow the correct steps:
   • Open Control Panel and select Mail.
   • Click on Show Profiles.
   • Click Add to create a new profile, and follow the prompts to set it up.
   • Make sure to select the new profile when launching Outlook.
2. Check for Compatibility Issues: Sometimes, Outlook may run in compatibility mode for a different operating system, which can cause it to not respond. You can check this by:
   • Right-click on the Outlook shortcut.
   • Select Properties and go to the Compatibility tab.
   • Ensure that no compatibility mode is selected.
3. Repair Outlook: You can try repairing your Outlook installation:
   • Go to Control Panel > Programs > Programs and Features.
   • Find Microsoft Office in the list, select it, and then click on Change.
   • Choose the Repair option and follow the instructions.
4. Check for Add-ins: Sometimes, third-party add-ins can cause Outlook to freeze or not respond. You can start Outlook in safe mode to see if this is the issue:
   • Press Windows + R, type outlook.exe /safe, and press Enter.
   • If Outlook opens in safe mode, consider disabling add-ins one by one to identify the culprit.
5. Create a New Windows User Profile: If the issue persists, it might be related to your Windows user profile. You can create a new Windows user account and see if Outlook works there.

If these steps do not resolve the issue, further investigation may be required to identify any underlying problems with your Outlook installation or Windows profile.

References:

• Outlook not responding error or Outlook freezes when you open a file or send mail
• Outlook is unable to start in Windows 7 or 8

Thanks for sharing the details, Stephen! Try to clear the Windows Search Index for Outlook.

If Outlook appears in Start menu but cannot be found via search, your search index may be corrupted only for your user profile.

How to rebuild the index:

• Open Control Panel → Indexing Options
• Click Advanced
• Under Troubleshooting, click Rebuild
• Restart your PC

This forces Windows to re-index apps, shortcuts, and Office entries tied to your user profile.

See if this helps. If you need further assistance just let me know.

Best regards,

Kimberly